Azacitidine improves the T-cell repertoire in patients with myelodysplastic syndromes and acute myeloid leukemia with multilineage dysplasia. Issue 9 (September 2015)

• Record Type: Journal Article
• Authors: Fozza, Claudio; Corda, Giovanna; Barraqueddu, Francesca; Virdis, Patrizia; Contini, Salvatore; Galleu, Antonio; Isoni, Antonella; Dore, Fausto; Angelucci, Emanuele; Longinotti, Maurizio
• Is Part Of: Leukemia research. Volume 39:Issue 9(2015:Sep.)
• Page Start: 957
• Page End: 963
• Publication Date: 2015-09
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.06.007
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">T-cell frequencies improve during Azacitidine therapy in MDS and AML with dysplasia.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">While on Azacitidine patients show a restoration of the CD4+ CDR3 diversity.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">The overall derangement of the T-cell repertoire gradually improves after Azacitidine.</p> </list-item> </list> </p> </sec> </abstract>