Boronate–Phenolic Network Capsules with Dual Response to Acidic pH and cis‐Diols. Issue 12 (18th June 2015)

• Record Type: Journal Article
• Authors: Guo, Junling; Sun, Huanli; Alt, Karen; Tardy, Blaise L.; Richardson, Joseph J.; Suma, Tomoya; Ejima, Hirotaka; Cui, Jiwei; Hagemeyer, Christoph E.; Caruso, Frank
• Is Part Of: Advanced healthcare materials. Volume 4:Issue 12(2015)
• Page Start: 1796
• Page End: 1801
• Publication Date: 2015-06-18
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201500332
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adhm201500332-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Dual‐responsive boronate–phenolic network (BPN) capsules</bold> are fabricated by the complexation of phenylborate and phenolic materials. The BPN capsules are stable in the presence of competing carbohydrates, but dissociate at acidic pH or in the presence of competing <italic>cis</italic>‐diols at physiological pH. This engineered capsule system provides a platform for a wide range of biological and biomedical applications. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj2g9cx7sm" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>