Is there a need for an alternative in the era of novel anticoagulants?. (September 2015)

• Record Type: Journal Article
• Authors: Ansell, Jack
• Is Part Of: Expert review of cardiovascular therapy. Volume 13:Number 9(2015)
• Page Start: 967
• Page End: 970
• Publication Date: 2015-09
• Subjects: Cardiovascular agents -- Research -- Periodicals; 616.12061
• Languages: English
• ISSNs: 1477-9072

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>With the development of the new direct oral anticoagulants, many of the unmet needs of the vitamin K antagonists were fulfilled, such as the absence of dietary interactions, few drug interactions, predictable effects and no need for monitoring. However, growing experience with the direct oral anticoagulants indicates there is still room for improvement. Developing antithrombotic agents that optimize their antithrombotic effect while producing little or no risk of bleeding is a long sought after goal. This and other enhanced attributes of candidate drugs are on the horizon.</p> </abstract>