Surgical margins and oncologic results after carcinoma of the external auditory canal. (25th May 2015)
- Record Type:
- Journal Article
- Title:
- Surgical margins and oncologic results after carcinoma of the external auditory canal. (25th May 2015)
- Main Title:
- Surgical margins and oncologic results after carcinoma of the external auditory canal
- Authors:
- Ihler, Friedrich
Koopmann, Mario
Weiss, Bernhard G.
Dröge, Leif Hendrik
Durisin, Martin
Christiansen, Hans
Weiß, Daniel
Canis, Martin
Wolff, Hendrik A. - Abstract:
- <abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="lary25381-sec-0001" sec-type="section"> <title>Objectives/Hypothesis</title> <p>External auditory canal cancer is rare and carries a poor prognosis. To date, only a few studies provide evidence for clinical decision making in multimodal treatment.</p> </sec> <sec id="lary25381-sec-0002" sec-type="section"> <title>Methods</title> <p>Retrospective chart review of 36 cases in three tertiary referral centers.</p> </sec> <sec id="lary25381-sec-0003" sec-type="section"> <title>Results</title> <p>Thirteen patients were treated by surgery alone, 18 by surgery with adjuvant chemoradiotherapy (CRT) and five by primary CRT. Clear surgical margins (R0) were obtained in 19 patients and positive margins (R1) in 12. The 5‐year overall survival and local control rates were 59.4% and 74.2% with R0 status versus 56.6% and 26.3% with R1 status. The 5‐year overall survival and local control rates were 46.2% and 70.7% with surgery alone, 78.1% and 43.2% with surgery and adjuvant CRT, and 25.0% and 80.0% with primary CRT.</p> </sec> <sec id="lary25381-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Surgery is integral to the management of external auditory canal cancer, whereas CRT is necessary as an adjuvant or primary treatment, depending on tumor stage.</p> </sec> <sec id="lary25381-sec-0005" sec-type="section"> <title>Level of Evidence</title> <p>4. <italic>Laryngoscope</italic>,<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="lary25381-sec-0001" sec-type="section"> <title>Objectives/Hypothesis</title> <p>External auditory canal cancer is rare and carries a poor prognosis. To date, only a few studies provide evidence for clinical decision making in multimodal treatment.</p> </sec> <sec id="lary25381-sec-0002" sec-type="section"> <title>Methods</title> <p>Retrospective chart review of 36 cases in three tertiary referral centers.</p> </sec> <sec id="lary25381-sec-0003" sec-type="section"> <title>Results</title> <p>Thirteen patients were treated by surgery alone, 18 by surgery with adjuvant chemoradiotherapy (CRT) and five by primary CRT. Clear surgical margins (R0) were obtained in 19 patients and positive margins (R1) in 12. The 5‐year overall survival and local control rates were 59.4% and 74.2% with R0 status versus 56.6% and 26.3% with R1 status. The 5‐year overall survival and local control rates were 46.2% and 70.7% with surgery alone, 78.1% and 43.2% with surgery and adjuvant CRT, and 25.0% and 80.0% with primary CRT.</p> </sec> <sec id="lary25381-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Surgery is integral to the management of external auditory canal cancer, whereas CRT is necessary as an adjuvant or primary treatment, depending on tumor stage.</p> </sec> <sec id="lary25381-sec-0005" sec-type="section"> <title>Level of Evidence</title> <p>4. <italic>Laryngoscope</italic>, 125:2107–2112, 2015</p> </sec> </abstract> … (more)
- Is Part Of:
- Laryngoscope. Volume 125:Number 9(2015:Sep.)
- Journal:
- Laryngoscope
- Issue:
- Volume 125:Number 9(2015:Sep.)
- Issue Display:
- Volume 125, Issue 9 (2015)
- Year:
- 2015
- Volume:
- 125
- Issue:
- 9
- Issue Sort Value:
- 2015-0125-0009-0000
- Page Start:
- 2107
- Page End:
- 2112
- Publication Date:
- 2015-05-25
- Subjects:
- Otolaryngology -- Periodicals
617.51005 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1531-4995/issues ↗
http://www.interscience.wiley.com/jpages/0023-852X ↗
http://www.laryngoscope.com ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/lary.25381 ↗
- Languages:
- English
- ISSNs:
- 0023-852X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 5156.200000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 4302.xml