In vitro study to simulate the intracardiac magnetohydrodynamic effect. Issue 3 (15th September 2014)

• Record Type: Journal Article
• Authors: Buchenberg, Waltraud B.; Mader, Wolfgang; Hoppe, Georg; Lorenz, Ramona; Menza, Marius; Büchert, Martin; Timmer, Jens; Jung, Bernd
• Is Part Of: Magnetic resonance in medicine. Volume 74:Issue 3(2015:Sep.)
• Page Start: 850
• Page End: 857
• Publication Date: 2014-09-15
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.25456
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm25456-sec-0001" sec-type="section"> <title>Purpose</title> <p>Blood flow causes induced voltages via the magnetohydrodynamic (MHD) effect distorting electrograms (EGMs) made during magnetic resonance imaging. To investigate the MHD effect in this context MHD voltages occurring inside the human heart were simulated in an in vitro model system inside a 1.5 T MR system.</p> </sec> <sec id="mrm25456-sec-0002" sec-type="section"> <title>Methods</title> <p>The model was developed to produce MHD signals similar to those produced by intracardiac flow and to acquire them using standard clinical equipment. Additionally, a new approach to estimate MHD distortions on intracardiac electrograms is proposed based on the analytical calculation of the MHD signal from MR phase contrast data.</p> </sec> <sec id="mrm25456-sec-0003" sec-type="section"> <title>Results</title> <p>The recorded MHD signals were similar in magnitude to intracardiac signals that would be measured by an electrogram of the left ventricle. The dependency of MHD signals on magnetic field strength and electrode separation was well reflected by an analytical model. MHD signals reconstructed from MR flow data were in excellent agreement with the MHD signal measured by clinical equipment.</p> </sec> <sec id="mrm25456-sec-0004" sec-type="section"> <title>Conclusion</title> <p>The in vitro model allows investigation of MHD effects on intracardiac electrograms. A phase contrast MR scan was successfully applied to characterize and estimate the MHD distortion on intracardiac signals allowing correction of these effects. Magn Reson Med 74:850–857, 2015. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>