High‐resolution variable‐density 3D cones coronary MRA. Issue 3 (14th July 2015)

• Record Type: Journal Article
• Authors: Addy, Nii Okai; Ingle, R. Reeve; Wu, Holden H.; Hu, Bob S.; Nishimura, Dwight G.
• Is Part Of: Magnetic resonance in medicine. Volume 74:Issue 3(2015:Sep.)
• Page Start: 614
• Page End: 621
• Publication Date: 2015-07-14
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.25803
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm25803-sec-0001" sec-type="section"> <title>Purpose</title> <p>To improve the spatial/temporal resolution of whole‐heart coronary MR angiography by developing a variable‐density (VD) 3D cones acquisition suitable for image reconstruction with parallel imaging and compressed sensing techniques.</p> </sec> <sec id="mrm25803-sec-0002" sec-type="section"> <title>Methods</title> <p>A VD 3D cones trajectory design incorporates both radial and spiral trajectory undersampling techniques to achieve higher resolution. This design is used to generate a VD 3D cones trajectory with 0.8 mm/66 ms isotropic spatial/temporal resolution, using a similar number of readouts as our previous fully sampled cones trajectory (1.2 mm/100 ms). Scans of volunteers and patients are performed to evaluate the performance of the VD trajectory, using non‐Cartesian L<sub>1</sub>‐ESPIRiT for high‐resolution image reconstruction.</p> </sec> <sec id="mrm25803-sec-0003" sec-type="section"> <title>Results</title> <p>With gridding reconstruction, the high‐resolution scans experience an expected drop in signal‐to‐noise and contrast‐to‐noise ratios, but with L<sub>1</sub>‐ESPIRiT, the apparent noise is substantially reduced. Compared with 1.2 mm images, in each volunteer, the L<sub>1</sub>‐ESPIRiT 0.8 mm images exhibit higher vessel sharpness values in the right and left anterior descending arteries.</p> </sec> <sec id="mrm25803-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Coronary MR angiography with isotropic submillimeter spatial resolution and high temporal resolution can be performed with VD 3D cones to improve the depiction of coronary arteries. Magn Reson Med 74:614–621, 2015. © 2015 Wiley Periodicals, Inc.</p> </sec> </abstract>