Non‐contrast‐enhanced peripheral angiography using a sliding interleaved cylinder acquisition. Issue 3 (9th September 2014)

• Record Type: Journal Article
• Authors: Kwon, Kie Tae; Kerr, Adam B.; Wu, Holden H.; Hu, Bob S.; Brittain, Jean H.; Nishimura, Dwight G.
• Is Part Of: Magnetic resonance in medicine. Volume 74:Issue 3(2015:Sep.)
• Page Start: 727
• Page End: 738
• Publication Date: 2014-09-09
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.25452
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm25452-sec-0001" sec-type="section"> <title>Purpose</title> <p>To develop a new sequence for non‐contrast‐enhanced peripheral angiography using a sliding interleaved cylinder (SLINCYL) acquisition.</p> </sec> <sec id="mrm25452-sec-0002" sec-type="section"> <title>Methods</title> <p>A venous saturation pulse was incorporated into a three‐dimensional magnetization‐prepared balanced steady‐state free precession sequence for non‐contrast‐enhanced peripheral angiography to improve artery‐vein contrast. The SLINCYL acquisition, which consists of a series of overlapped thin slabs for volumetric coverage similar to the original sliding interleaved <italic>k</italic><sub><italic>y</italic></sub> (SLINKY) acquisition, was used to evenly distribute the venous‐suppression effects over the field of view. In addition, the thin‐slab‐scan nature of SLINCYL and the centric‐ordered sampling geometry of its readout trajectory were exploited to implement efficient fluid‐suppression and parallel imaging schemes. The sequence was tested in healthy subjects and a patient.</p> </sec> <sec id="mrm25452-sec-0003" sec-type="section"> <title>Results</title> <p>Compared to a multiple overlapped thin slab acquisition, both SLINKY and SLINCYL suppressed the venetian blind artifacts and provided similar artery‐vein contrast. However, SLINCYL achieved this with shorter scan times and less noticeable artifacts from k‐space amplitude modulation than SLINKY. The fluid‐suppression and parallel imaging schemes were also validated. A patient study using the SLINCYL‐based sequence well identified stenoses at the superficial femoral arteries, which were also confirmed with digital subtraction angiography.</p> </sec> <sec id="mrm25452-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Non‐contrast‐enhanced angiography using SLINCYL can provide angiograms with improved artery‐vein contrast in the lower extremities. Magn Reson Med 74:727–738, 2015. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>