Candidate biomarkers in heart failure with reduced and preserved ejection fraction. (June 2015)

• Record Type: Journal Article
• Authors: Sinning, Christoph; Zengin, Elvin; Zeller, Tanja; Schnabel, Renate B.; Blankenberg, Stefan; Westermann, Dirk
• Is Part Of: Biomarkers. Volume 20:Number 4(2015)
• Page Start: 258
• Page End: 265
• Publication Date: 2015-06
• Subjects: Biochemical markers -- Periodicals; 610.28
• Languages: English
• ISSNs: 1354-750X

Abstract

<abstract> <title>Abstract</title> <p> <italic>Context</italic>: Patients presenting with heart failure symptoms are categorized into heart failure (HF) with reduced and preserved ejection fraction.</p> <p> <italic>Objective</italic>: Aim is to investigate the additional use of candidate biomarkers to characterize patients with either sub-type of HF.</p> <p> <italic>Methods</italic>: Literature search was conducted in the electronic databases MEDLINE and Cochrane Central Register of Controlled Trials from inception through November 2014.</p> <p> <italic>Results</italic>: The results of 47 diseased and general population cohorts were included.</p> <p> <italic>Conclusion</italic>: Current studies could outline the additional use of candidate biomarkers especially GDF-15, MR-proADM and high-sensitive determined troponin, although major outcome studies are still missing.</p> </abstract>