Machine‐Assisted Organic Synthesis. Issue 35 (16th July 2015)

• Record Type: Journal Article
• Authors: Ley, Steven V.; Fitzpatrick, Daniel E.; Myers, Rebecca M.; Battilocchio, Claudio; Ingham, Richard. J.
• Is Part Of: Angewandte Chemie international edition. Volume 54:Issue 35(2015)
• Page Start: 10122
• Page End: 10136
• Publication Date: 2015-07-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201501618
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors. In the rapidly changing, multivariant environment of the research laboratory, equipment needs to be modular to accommodate high and low temperatures and pressures, enzymes, multiphase systems, slurries, gases, and organometallic compounds. Additional technologies have been developed to facilitate more specialized reaction techniques such as electrochemical and photochemical methods. All of these areas create both opportunities and challenges during adoption as enabling technologies.</p> </abstract>