Construction of Versatile and Functional Nanostructures Derived from CO2‐based Polycarbonates1. Issue 35 (15th July 2015)

• Record Type: Journal Article
• Authors: Wang, Yanyan; Fan, Jingwei; Darensbourg, Donald J.
• Is Part Of: Angewandte Chemie international edition. Volume 54:Issue 35(2015)
• Page Start: 10206
• Page End: 10210
• Publication Date: 2015-07-15
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201505076
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The construction of amphiphilic polycarbonates through epoxides/CO₂ coupling is a challenging aim to provide more diverse CO₂‐based functional materials. In this report, we demonstrate the facile preparation of diverse and functional nanoparticles derived from a CO₂‐based triblock polycarbonate system. By the judicious use of water as chain‐transfer reagent in the propylene oxide/CO₂ polymerization, poly(propylene carbonate (PPC) diols are successfully produced and serve as macroinitiators in the subsequent allyl glycidyl ether/CO₂ coupling reaction. The resulting ABA triblock polycarbonate can be further functionalized with various thiols by radical mediated thiol–ene click chemistry, followed by self‐assembly in deionized water to construct a versatile and functional nanostructure system. This class of amphiphilic polycarbonates could embody a powerful platform for biomedical applications.</p> </abstract>