Fast single‐beam‐CARS imaging scheme based on in silico optimization of excitation phases. (20th May 2015)

• Record Type: Journal Article
• Authors: Wipfler, Alexander; Buckup, Tiago; Motzkus, Marcus; Joubert, Pierre; Lavorel, Bruno; Kiefer, Johannes; Moger, Julian
• Is Part Of: Journal of Raman spectroscopy. Volume 46:Number 8(2015:Aug.)
• Page Start: 679
• Page End: 682
• Publication Date: 2015-05-20
• Subjects: Raman spectroscopy -- Periodicals; 535.846
• DOI: 10.1002/jrs.4703
• Languages: English
• ISSNs: 0377-0486

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>A novel scheme for the detection of known species with single‐beam coherent anti‐Stokes Raman scattering spectroscopy is presented in theory and simulations. The introduction of a simulation tool based on fast Fourier transforms allows a purely numerical optimization of excitation phases <italic>ex situ</italic>, to which we refer to as <italic>in silico</italic> optimization. Such an optimal phase is based on the encoding of vibrational resonances in specific spectral detection windows using multichannel measurements. The presented detection scheme offers a route to fast chemical selective imaging with high contrast and simplified data acquisition, thereby avoiding photodamage of sensitive biological samples. Copyright © 2015 John Wiley &amp; Sons, Ltd.</p> </abstract>