A Biomimetic Core–Shell Platform for Miniaturized 3D Cell and Tissue Engineering. (12th May 2015)

• Record Type: Journal Article
• Authors: Agarwal, Pranay; Choi, Jung Kyu; Huang, Haishui; Zhao, Shuting; Dumbleton, Jenna; Li, Jianrong; He, Xiaoming
• Is Part Of: Particle and particle systems characterization. Volume 32:Number 8(2015:Aug.)
• Page Start: 809
• Page End: 816
• Publication Date: 2015-05-12
• Subjects: Particles -- Periodicals; 620.43
• DOI: 10.1002/ppsc.201500025
• Languages: English
• ISSNs: 0934-0866

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="ppsc201500025-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>This article describes a biomimetic core–shell platform</bold> with a collagen‐based core and an alginate hydrogel shell for cell and tissue culture. With this system, chemical and physical properties of extracellular matrix (ECM) in the core microenvironment can be controlled to regulate proliferation and development of cells/tissues under miniaturized 3D culture. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj2f6z67b9" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>