Malignant Eccrine Spiradenoma of the Face. Issue 5 (July 2015)

• Record Type: Journal Article
• Authors: Nyame, Theodore T.; Mattos, David; Lian, Christine G.; Granter, Scott R.; Laga, Alvaro C.; Caterson, E.J.
• Is Part Of: Journal of craniofacial surgery. Volume 26:Issue 5(2015)
• Publication Date: 2015-07
• Subjects: Facial bones -- Surgery -- Periodicals; Skull -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.52
• DOI: 10.1097/SCS.0000000000001857
• Languages: English
• ISSNs: 1049-2275

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Abstract</title> <p>Malignant eccrine spiradenoma, or spiradenocarcinoma, is an exceedingly rare sweat-gland tumor, with only 102 reported cases. Low-grade carcinomas are especially rare with only a few cases reported. Because of the limited number of case reports, the biologic behavior of low-grade malignant eccrine spiradenoma is poorly understood and no evidence-based therapeutic approach is established. Here, the authors report a 29-year-old woman who presented with a history of left-sided facial lesions present since the age of 2 months. Histopathologic examination revealed multiple benign spiradenomas, several of which showed foci of low-grade malignant transformation evidenced by loss of the characteristic 2-cell population seen in the benign tumor component. Included are the clinical presentation, histopathologic description, and surgical decision making in an effort to guide recognition of this rare entity.</p> </sec> </abstract>