PH-operated hybrid silica nanoparticles with multiple H-bond stoppers for colon cancer therapy1. Issue 80 (2nd September 2015)

• Record Type: Journal Article
• Authors: Théron, C.; Gallud, A.; Giret, S.; Maynadier, M.; Grégoire, D.; Puche, P.; Jacquet, E.; Pop, G.; Sgarbura, O.; Bellet, V.; Hibner, U.; Zink, J. I.; Garcia, M.; Wong Chi Man, M.; Carcel, C.; Gary-Bobo, M.
• Is Part Of: RSC advances. Volume 5:Issue 80(2015)
• Page Start: 64932
• Page End: 64936
• Publication Date: 2015-09-02
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra09891b
• Languages: English
• ISSNs: 2046-2069

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2ds7ptvc" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Controlled delivery of a chemotherapeutic drug from pH-sensitive hybrid silica nanocarriers efficiently targets colon carcinoma cells. The drug, blocked by cyanuric acid as stopper, is autonomously released inside the cancer cells.</p> </abstract>