Caffeine ameliorates high energy diet-induced hepatic steatosis: sirtuin 3 acts as a bridge in the lipid metabolism pathway1. Issue 8 (5th August 2015) - Zhang, Shi-Jie
Abstract We demonstrate that caffeine could improve HED-induced hepatic steatosis by promoting lipid metabolism via the cAMP/CREB/SIRT3/AMPK/ACC pathway. SIRT3 acts as a molecular bridge connecting caffeine and lipid metabolism.