PPARα agonists based on stilbene and its bioisosteres: biological evaluation and docking studies1. Issue 8 (5th August 2015)

• Record Type: Journal Article
• Authors: De Filippis, Barbara; Agamennone, Mariangela; Ammazzalorso, Alessandra; Bruno, Isabella; D'Angelo, Alessandra; Di Matteo, Mauro; Fantacuzzi, Marialuigia; Giampietro, Letizia; Giancristofaro, Antonella; Maccallini, Cristina; Amoroso, Rosa
• Is Part Of: MedChemComm. Volume 6:Issue 8(2015:Aug.)
• Page Start: 1513
• Page End: 1517
• Publication Date: 2015-08-05
• Subjects: Pharmaceutical chemistry -- Periodicals; 615.19
• DOI: 10.1039/c5md00151j
• Languages: English
• ISSNs: 2040-2503

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2df3f7tq" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A new series of gemfibrozil analogues conjugated with <italic>trans</italic>-stilbene were synthesized and evaluated with the aim of developing new PPARα agonists.</p> </abstract>