The relevance of ADCC for EGFR targeting: A review of the literature and a clinically-applicable method of assessment in patients. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Monteverde, Martino; Milano, Gerard; Strola, Giuliana; Maffi, Monica; Lattanzio, Laura; Vivenza, Daniela; Tonissi, Federica; Merlano, Marco; Lo Nigro, Cristiana
• Is Part Of: Critical reviews in oncology/hematology. Volume 95:Issue 2(2015)
• Page Start: 179
• Page End: 190
• Publication Date: 2015-08
• Subjects: Oncology -- Periodicals; Hematology -- Periodicals; 616.994
• DOI: 10.1016/j.critrevonc.2015.02.014
• Languages: English
• ISSNs: 1040-8428

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005"> <italic>Ex vivo</italic> ADCC answer can be related to donor effector cell.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">LDH assay could be used for ADCC testing.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">We exclude frozen PBMC as best candidates for ADCC test.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">In chemotherapeutic regimen a fixed number of NK should be evaluated for ADCC.</p> </list-item> </list> </p> </sec> </abstract>