Human Papillomavirus-related tumours of the oropharynx display a lower tumour hypoxia signature. Issue 9 (September 2015)

• Record Type: Journal Article
• Authors: Hanns, Elodie; Job, Sylvie; Coliat, Pierre; Wasylyk, Christine; Ramolu, Ludivine; Pencreach, Erwan; Suarez-Carmona, Meggy; Herfs, Michael; Ledrappier, Sonia; Macabre, Christine; Abecassis, Joseph; Wasylyk, Bohdan; Jung, Alain C.
• Is Part Of: Oral oncology. Volume 51:Issue 9(2015:Sep.)
• Page Start: 848
• Page End: 856
• Publication Date: 2015-09
• Subjects: Mouth -- Cancer -- Periodicals; Mouth -- Tumors -- Periodicals; Mouth Diseases -- Periodicals; Mouth Neoplasms -- Periodicals; Bouche -- Cancer -- Périodiques; Bouche -- Tumeurs -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9943105
• DOI: 10.1016/j.oraloncology.2015.06.003
• Languages: English
• ISSNs: 1368-8375

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st005">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0005">HPV-positive and -negative HNSCC cells lines adapt differently to hypoxia.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0010">HPV-positive xenografts display less hypoxic area/cells.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0015">HPV-positive OSCC have a lower hypoxia status.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0020">HPV-positive OSCC display increased tumour angiogenesis.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0025">Improved response to therapy could be linked to these hypoxia properties.</p> </list-item> </list> </p> </sec> </abstract>