The evolution of IL-4 and IL-13 and their receptor subunits. Issue 1 (September 2015)

• Record Type: Journal Article
• Authors: Wang, Tiehui; Secombes, Christopher J.
• Is Part Of: Cytokine. Volume 75:Issue 1(2015)
• Page Start: 8
• Page End: 13
• Publication Date: 2015-09
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.04.012
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author" id="ab005"> <title id="st005">Abstract</title> <sec> <p id="sp0005">This review will outline what is known about the origins and evolution of type 2 cytokines and their receptors in vertebrates. It takes advantage of the recent advances made in gene identification from the many vertebrate genomes that have now been sequenced. It will also describe what functional studies have been performed to date, giving clues to the role of these molecules and signalling pathways in non-mammalian vertebrates.</p> </sec> </abstract>