Deciphering the crosstalk among IL-1 and IL-10 family cytokines in intestinal immunity. Issue 8 (August 2015)

• Record Type: Journal Article
• Authors: Manzanillo, Paolo; Eidenschenk, Celine; Ouyang, Wenjun
• Is Part Of: Trends in immunology. Volume 36:Issue 8(2015)
• Page Start: 471
• Page End: 478
• Publication Date: 2015-08
• Subjects: Immunology -- Periodicals; 571.96
• DOI: 10.1016/j.it.2015.06.003
• Languages: English
• ISSNs: 1471-4906

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">IL-1 and IL-10 family cytokines form a regulatory network within the gut.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">IL-22 from ILCs regulates IL-18 expression in IECs during infection or TLR stimulation.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Microbiota induce IL-1β production by myeloid cells, which enhances IL-22 production by ILCs.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">IL-10 from Treg cells regulates IL-1β by myeloid cells and the development of colitis.</p> </list-item> </list> </p> </sec> </abstract>