Organocatalyzed Asymmetric Conjugate Addition of Heteroaryl and Aryl Trifluoroborates: a Synthetic Strategy for Discoipyrrole D1. (12th June 2015)
- Record Type:
- Journal Article
- Title:
- Organocatalyzed Asymmetric Conjugate Addition of Heteroaryl and Aryl Trifluoroborates: a Synthetic Strategy for Discoipyrrole D1. (12th June 2015)
- Main Title:
- Organocatalyzed Asymmetric Conjugate Addition of Heteroaryl and Aryl Trifluoroborates: a Synthetic Strategy for Discoipyrrole D1
- Authors:
- Shih, Jiun‐Le
Nguyen, Thien S.
May, Jeremy A. - Abstract:
- <abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Bis‐heteroaryl or bis‐aryl stereocenters were formed by an organocatalytic enantioselective conjugate addition using the respective trifluoroborate salts as nucleophiles. Control studies suggested that fluoride dissociation is necessary in the anhydrous conditions. This strategy is applicable to the synthesis of discoipyrrole D, an inhibitor of BR5 fibroblast migration.</p> </abstract>
- Is Part Of:
- Angewandte Chemie. Volume 127:Number 34(2015)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 127:Number 34(2015)
- Issue Display:
- Volume 127, Issue 34 (2015)
- Year:
- 2015
- Volume:
- 127
- Issue:
- 34
- Issue Sort Value:
- 2015-0127-0034-0000
- Page Start:
- 10069
- Page End:
- 10073
- Publication Date:
- 2015-06-12
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201503528 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 4063.xml