DETECTION OF MALNUTRITION IN PATIENTS UNDERGOING MAINTENANCE HAEMODIALYSIS: A QUANTITATIVE DATA ANALYSIS ON 12 PARAMETERS. Issue 3 (21st April 2015)

• Record Type: Journal Article
• Authors: Nafzger, Sonja; Fleury, Lea‐Angelica; Uehlinger, Dominik E.; Plüss, Petra; Scura, Ninetta; Kurmann, Silvia
• Is Part Of: Journal of renal care. Volume 41:Issue 3(2015:Sep.)
• Page Start: 168
• Page End: 176
• Publication Date: 2015-04-21
• Subjects: Kidneys -- Diseases -- Nursing -- Periodicals; Hemodialysis -- Periodicals; Kidney Diseases -- nursing -- Periodicals; Renal Replacement Therapy -- nursing -- Periodicals; 616.61
• DOI: 10.1111/jorc.12125
• Languages: English
• ISSNs: 1755-6678

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>SUMMARY</title> <sec id="jorc12125-sec-0001" sec-type="section"> <title>Background</title> <p>Protein‐energy‐malnutrition (PEM) is common in people with end stage kidney disease (ESKD) undergoing maintenance haemodialysis (MHD) and correlates strongly with mortality. To this day, there is no gold standard for detecting PEM in patients on MHD.</p> </sec> <sec id="jorc12125-sec-0002" sec-type="section"> <title>Aim of Study</title> <p>The aim of this study was to evaluate if Nutritional Risk Screening 2002 (NRS‐2002), handgrip strength measurement, mid‐upper arm muscle area (MUAMA), triceps skin fold measurement (TSF), serum albumin, normalised protein catabolic rate (nPCR), Kt/V and eKt/V, dry body weight, body mass index (BMI), age and time since start on MHD are relevant for assessing PEM in patients on MHD.</p> </sec> <sec id="jorc12125-sec-0003" sec-type="section"> <title>Methods</title> <p>The predictive value of the selected parameters on mortality and mortality or weight loss of more than 5% was assessed. Quantitative data analysis of the 12 parameters in the same patients on MHD in autumn 2009 (n = 64) and spring 2011 (n = 40) with paired statistical analysis and multivariate logistic regression analysis was performed.</p> </sec> <sec id="jorc12125-sec-0004" sec-type="section"> <title>Results</title> <p>Paired data analysis showed significant reduction of dry body weight, BMI and nPCR. Kt/V<sub>tot</sub> did not change, eKt/v and hand grip strength measurements were significantly higher in spring 2011. No changes were detected in TSF, serum albumin, NRS‐2002 and MUAMA. Serum albumin was shown to be the only predictor of death and of the combined endpoint "death or weight loss of more than 5%".</p> </sec> <sec id="jorc12125-sec-0005" sec-type="section"> <title>Conclusion</title> <p>We now screen patients biannually for serum albumin, nPCR, Kt/V, handgrip measurement of the shunt‐free arm, dry body weight, age and time since initiation of MHD.</p> </sec> </abstract>