Successful treatment with sirolimus for an angiomyolipoma mimicking renal cell carcinoma in a transplanted kidney. (6th April 2015)

• Record Type: Journal Article
• Authors: Chiu, Hsien‐Fu; Wen, Mei‐Chin; Li, Jian‐Ri; Ho, Hao‐Chung; Shu, Kuo‐Hsiung
• Is Part Of: Transplant international. Volume 28:Number 9(2015:Sep.)
• Page Start: 1116
• Page End: 1120
• Publication Date: 2015-04-06
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; 617.95405
• DOI: 10.1111/tri.12567
• Languages: English
• ISSNs: 0934-0874

Abstract

<abstract abstract-type="main" id="tri12567-abs-0001"> <title>Summary</title> <p>Angiomyolipoma (AML) is a benign mesenchymal tumor composed of blood vessels, smooth muscle, and mature adipose tissue. AMLs in the kidney allografts are rare. We report a case of AML that was incidentally found 1 year after transplantation. Abdominal computed tomography showed a 4‐cm renal tumor with contrast enhancement and an early washout pattern, resembling a renal cell carcinoma. Tumor biopsy proved a lipid‐poor AML. Tumor diameter decreased to 2.4 cm after 6 months of treatment with sirolimus. Sirolimus not only reduces tumor size, but also benefits a transplant patient who needs immunosuppression.</p> </abstract>