Drug Targeting: Active Targeting of Sorafenib: Preparation, Characterization, and In Vitro Testing of Drug‐Loaded Magnetic Solid Lipid Nanoparticles (Adv. Healthcare Mater. 11/2015). Issue 11 (August 2015)

• Record Type: Journal Article
• Authors: Grillone, Agostina; Riva, Eugenio Redolfi; Mondini, Alessio; Forte, Claudia; Calucci, Lucia; Innocenti, Claudia; de Julian Fernandez, Cesar; Cappello, Valentina; Gemmi, Mauro; Moscato, Stefania; Ronca, Francesca; Sacco, Rodolfo; Mattoli, Virgilio; Ciofani, Gianni
• Is Part Of: Advanced healthcare materials. Volume 4:Issue 11(2015)
• Page Start: 1734
• Page End: 1734
• Publication Date: 2015-08
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201570068
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adhm201570068-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Sorafenib‐loaded magnetic solid lipid nanoparticles are highly internalized by HepG2 human hepatocarcinoma cells. As described by A. Grillone, G. Ciofani, and co‐workers on page 1681, the uptake of the nanoparticles can be directed by modulating their accumulation through an external magnetic field, thus focusing the drug effects at a desired site. <graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgj2cqns45m" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></p> </abstract>