Gold‐Catalyzed Cyclization Leads to a Bridged Tetracyclic Indolenine that Represses β‐Lactam Resistance1. Issue 33 (12th June 2015)
- Record Type:
- Journal Article
- Title:
- Gold‐Catalyzed Cyclization Leads to a Bridged Tetracyclic Indolenine that Represses β‐Lactam Resistance1. Issue 33 (12th June 2015)
- Main Title:
- Gold‐Catalyzed Cyclization Leads to a Bridged Tetracyclic Indolenine that Represses β‐Lactam Resistance1
- Authors:
- Xu, Wenqing
Wang, Wei
Wang, Xiang - Abstract:
- <abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A gold‐catalyzed desilylative cyclization was developed for facile synthesis of bridged tetracyclic indolenines, a common motif in many natural indole alkaloids. An antimicrobial screen of the cyclization products identified one compound which selectively potentiates β‐lactam antibiotics in methicillin‐resistant <italic>S. aureus</italic> (MRSA), and re‐sensitizes a variety of MRSA strains to β‐lactams.</p> </abstract>
- Is Part Of:
- Angewandte Chemie international edition. Volume 54:Issue 33(2015)
- Journal:
- Angewandte Chemie international edition
- Issue:
- Volume 54:Issue 33(2015)
- Issue Display:
- Volume 54, Issue 33 (2015)
- Year:
- 2015
- Volume:
- 54
- Issue:
- 33
- Issue Sort Value:
- 2015-0054-0033-0000
- Page Start:
- 9546
- Page End:
- 9549
- Publication Date:
- 2015-06-12
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3773 ↗
http://www.interscience.wiley.com/jpages/1433-7851 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/anie.201503736 ↗
- Languages:
- English
- ISSNs:
- 1433-7851
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 3980.xml