Discrimination of the prochiral hydrogens at the C-2 position of n-alkanes by the methane/ammonia monooxygenase family proteins1. Issue 30 (14th August 2015)

• Record Type: Journal Article
• Authors: Miyaji, Akimitsu; Miyoshi, Teppei; Motokura, Ken; Baba, Toshihide
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 30(2015)
• Page Start: 8261
• Page End: 8270
• Publication Date: 2015-08-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00640f
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2b2w1k7q" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The substrate binding site of AMO/pMMO family proteins can discriminate between the prochiral hydrogens at the C-2 position of <italic>n</italic>-alkanes. We predict that at least one of the three amino acid residues at the di-copper site affects the discriminating ability of the family proteins.</p> </abstract>