(E)- and (Z)-stereodefined enol phosphonates derived from β-ketoesters: stereocomplementary synthesis of fully-substituted α, β-unsaturated esters1. Issue 30 (14th August 2015)

• Record Type: Journal Article
• Authors: Nakatsuji, Hidefumi; Ashida, Yuichiro; Hori, Hiroshi; Sato, Yuka; Honda, Atsushi; Taira, Mayu; Tanabe, Yoo
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 30(2015)
• Page Start: 8205
• Page End: 8210
• Publication Date: 2015-08-14
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob01097g
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj2b2w1m2g" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A versatile, robust, and stereocomplementary synthesis of fully-substituted (<italic>E</italic>)- and (<italic>Z</italic>)-stereodefined α, β-unsaturated esters <bold>3</bold> from accessible α-substituted β-ketoesters <bold>1</bold><italic>via</italic> (<italic>E</italic>)- and (<italic>Z</italic>)-enol phosphonates was achieved.</p> </abstract>