Ring closing metathesis reactions of α-methylene-β-lactams: application to the synthesis of a simplified phyllostictine analogue with herbicidal activity1. Issue 28 (28th July 2015)

• Record Type: Journal Article
• Authors: Coe, Samuel; Pereira, Nicole; Geden, Joanna V.; Clarkson, Guy J.; Fox, David J.; Napier, Richard M.; Neve, Paul; Shipman, Michael
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 28(2015)
• Page Start: 7655
• Page End: 7663
• Publication Date: 2015-07-28
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00890e
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj26bckp4d" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The first RCM reactions of α-methylene-β-lactams are used to construct strained macrocycles that mimic elements of phyllostictine A.</p> </abstract>