Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors. Issue 72 (6th August 2015)
- Record Type:
- Journal Article
- Title:
- Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors. Issue 72 (6th August 2015)
- Main Title:
- Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors
- Authors:
- Silva, T.
Borges, F.
Edraki, N.
Alizadeh, M.
Miri, R.
Saso, L.
Firuzi, O. - Abstract:
- <abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj26bbztqq" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The most active hydroxycinnamic acid derivative, caffeic acid diethyl ester (CA-DE), demonstrated 88.5/30.5% inhibition at 100/20 μM against COX-2 and negligible COX-1 inhibitory effect. CA-DE showed preferred interactions with COX-2 active site.</p> </abstract>
- Is Part Of:
- RSC advances. Volume 5:Issue 72(2015)
- Journal:
- RSC advances
- Issue:
- Volume 5:Issue 72(2015)
- Issue Display:
- Volume 5, Issue 72 (2015)
- Year:
- 2015
- Volume:
- 5
- Issue:
- 72
- Issue Sort Value:
- 2015-0005-0072-0000
- Page Start:
- 58902
- Page End:
- 58911
- Publication Date:
- 2015-08-06
- Subjects:
- Chemistry -- Periodicals
540.5 - Journal URLs:
- http://pubs.rsc.org/en/Journals/JournalIssues/RA ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c5ra08692b ↗
- Languages:
- English
- ISSNs:
- 2046-2069
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8036.750300
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 3730.xml