Synthesis and biological evaluation of α-sulfonamido-N-adamantanecarboxamide derivatives as 11β-HSD1 inhibitors. Issue 7 (8th July 2015)

• Record Type: Journal Article
• Authors: Kim, Young Hoon; Kang, Seung Kyu; Lee, Gwi Bin; Lee, Kyu Myung; Kumar, Jaladi Ashok; Kim, Ki Young; Rhee, Sang Dal; Joo, Jeongmin; Bae, Myung Ae; Lee, Won Koo; Ahn, Jin Hee
• Is Part Of: MedChemComm. Volume 6:Issue 7(2015:Jul.)
• Page Start: 1360
• Page End: 1369
• Publication Date: 2015-07-08
• Subjects: Pharmaceutical chemistry -- Periodicals; 615.19
• DOI: 10.1039/c5md00096c
• Languages: English
• ISSNs: 2040-2503

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj26874z79" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A series of α-sulfonamido-<italic>N</italic>-adamantanecarboxamide derivatives was synthesized and shown to have good <italic>in vitro</italic> and <italic>ex vivo</italic> efficacy.</p> </abstract>