Synthesis and properties of 2′-O, 4′-C-spirocyclopropylene bridged nucleic acid (scpBNA), an analogue of 2′, 4′-BNA/LNA bearing a cyclopropane ring1. Issue 47 (14th June 2015)

Record Type:
Journal Article
Title:
Synthesis and properties of 2′-O, 4′-C-spirocyclopropylene bridged nucleic acid (scpBNA), an analogue of 2′, 4′-BNA/LNA bearing a cyclopropane ring1. Issue 47 (14th June 2015)
Main Title:
Synthesis and properties of 2′-O, 4′-C-spirocyclopropylene bridged nucleic acid (scpBNA), an analogue of 2′, 4′-BNA/LNA bearing a cyclopropane ring1
Authors:
Yamaguchi, Takao
Horiba, Masahiko
Obika, Satoshi
Abstract:
<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1zk76vvc" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The scpBNA-modified oligonucleotides exhibit excellent duplex-forming ability toward the complementary ssRNA, and dramatically increased resistance to nuclease activity compared to their 2′, 4′-BNA/LNA-modified counterparts.</p> </abstract>
Is Part Of:
Chemical communications. Volume 51:Issue 47(2015)
Journal:
Chemical communications
Issue:
Volume 51:Issue 47(2015)
Issue Display:
Volume 51, Issue 47 (2015)
Year:
2015
Volume:
51
Issue:
47
Issue Sort Value:
2015-0051-0047-0000
Page Start:
9737
Page End:
9740
Publication Date:
2015-06-14
Subjects:
Chemistry -- Periodicals
540
Journal URLs:
http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗
DOI:
10.1039/c5cc02024g ↗
Languages:
English
ISSNs:
1359-7345
Deposit Type:
Legaldeposit
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗
Physical Locations:
British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store
Ingest File:
4382.xml