Synthesis of N-benzyl-N-phenylthiophene-2-carboxamide analogues as a novel class of enterovirus 71 inhibitors1. Issue 68 (25th July 2015)

• Record Type: Journal Article
• Authors: Pan, Jiawei; Han, Xin; Sun, Ningyuan; Wu, Haoming; Lin, Dandan; Tien, Po; Zhou, Hai-Bing; Wu, Shuwen
• Is Part Of: RSC advances. Volume 5:Issue 68(2015)
• Page Start: 55100
• Page End: 55108
• Publication Date: 2015-07-25
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c5ra07286g
• Languages: English
• ISSNs: 2046-2069

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1jkm28v1" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A series of <italic>N</italic>-benzyl-<italic>N</italic>-phenylthiophene-2-carboxamide analogues were identified as novel human enterovirus 71 inhibitors with EC₅₀ values up to 1.42 μM.</p> </abstract>