Exploring the potential of gold(iii) cyclometallated compounds as cytotoxic agents: variations on the C^N theme1. Issue 26 (14th July 2015)

• Record Type: Journal Article
• Authors: Bertrand, B.; Spreckelmeyer, S.; Bodio, E.; Cocco, F.; Picquet, M.; Richard, P.; Le Gendre, P.; Orvig, C.; Cinellu, M. A.; Casini, A.
• Is Part Of: Dalton transactions. Volume 44:Issue 26(2015)
• Page Start: 11911
• Page End: 11918
• Publication Date: 2015-07-14
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c5dt01023c
• Languages: English
• ISSNs: 1477-9226

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1c6gv76w" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />New (C^N) cyclometallated Au(<sc>iii</sc>) complexes with cytotoxic properties shown to be potent inhibitors of the zinc finger protein PARP-1.</p> </abstract>