A shortcut to high-affinity Ga-68 and Cu-64 radiopharmaceuticals: one-pot click chemistry trimerisation on the TRAP platform1. Issue 24 (28th June 2015)

• Record Type: Journal Article
• Authors: Baranyai, Zsolt; Reich, Dominik; Vágner, Adrienn; Weineisen, Martina; Tóth, Imre; Wester, Hans-Jürgen; Notni, Johannes
• Is Part Of: Dalton transactions. Volume 44:Issue 24(2015)
• Page Start: 11137
• Page End: 11146
• Publication Date: 2015-06-28
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c5dt00576k
• Languages: English
• ISSNs: 1477-9226

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1018j9tk" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The kinetic inertness profile of Cu(<sc>ii</sc>) complexes of TRAP-conjugates enables simple Cu(<sc>ii</sc>) removal after click functionalisation and confirms their suitability for Cu-64-PET.</p> </abstract>