Anticancer effect and mechanism of a Se-modified porphyrin Au(III) complex. Issue 17 (1st September 2015)

• Record Type: Journal Article
• Authors: Yang, Feng-Rui; Li, Yue; Zhang, Xiao-Hong; Wang, Meng; Guo, Hong-Rui; Ruan, Wen-Juan
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 25:Issue 17(2015)
• Page Start: 3592
• Page End: 3596
• Publication Date: 2015-09-01
• Subjects: Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2015.06.075
• Languages: English
• ISSNs: 0960-894X

Abstract

<abstract xml:lang="en" abstract-type="graphical" id="ab005"> <title id="st015">Graphical abstract</title> <sec> <p id="sp0005">By inducing mitochondrial-dependent apoptosis and arresting cell cycle, a Se modified porphyrin Au(III) complex, [AuTPP-Se]Cl, exhibits high antiproliferative activity to all the six tested cancer cells. <fig id="f0025" position="anchor"><graphic position="anchor" xlink:href="ark:/27927/pgj28j8q5zq" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></fig></p> </sec> </abstract>