Modeling the long-term antibody response of a hepatitis E vaccine. Issue 33 (7th August 2015)

• Record Type: Journal Article
• Authors: Chen, Shu; Zhou, Zi; Wei, Fei-Xue; Huang, Shou-Jie; Tan, Zhong; Fang, Ya; Zhu, Feng-Cai; Wu, Ting; Zhang, Jun; Xia, Ning-Shao
• Is Part Of: Vaccine. Volume 33:Issue 33(2015)
• Page Start: 4124
• Page End: 4129
• Publication Date: 2015-08-07
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.06.050
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title id="sect0005">Highlights</title> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">This is the first report regarding the long-term antibody response modeling of HEV 239 vaccine.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Two models used in this study were fit well using the anti-HEV IgG data from 1278 baseline seronegative vaccine recipients.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">The HEV 239 vaccine is predicted to provide from 8 years to near life-long persistence of anti-HEV IgG above detectable levels.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Model predictions in this study are based on conservative mathematical assumptions.</p> </list-item> </list> </p> </sec> </abstract>