Single-molecule insights into mRNA dynamics in neurons. Issue 8 (August 2015)

• Record Type: Journal Article
• Authors: Buxbaum, Adina R.; Yoon, Young J.; Singer, Robert H.; Park, Hye Yoon
• Is Part Of: Trends in cell biology. Volume 25:Issue 8(2015)
• Page Start: 468
• Page End: 475
• Publication Date: 2015-08
• Subjects: Cytology -- Periodicals; Cytology -- Research -- Periodicals; 571.6
• DOI: 10.1016/j.tcb.2015.05.005
• Languages: English
• ISSNs: 0962-8924

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">mRNA localization into neuronal processes and localized translation is an efficient mechanism of local protein delivery in neurons due to their long processes and synaptic function.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Single-mRNA studies in neurons illustrate the diverse and stochastic nature of mRNA trafficking into neuronal processes.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Single-molecule imaging of endogenous mRNA has illuminated a novel and unexpected understanding of mRNA dynamics.</p> </list-item> </list> </p> </sec> </abstract>