MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer. Issue 2 (1st July 2015)

• Record Type: Journal Article
• Authors: Chen, Di; Guo, Weijie; Qiu, Zhaoping; Wang, Qifeng; Li, Yan; Liang, Linhui; Liu, Li; Huang, Shenglin; Zhao, Yingjun; He, Xianghuo
• Is Part Of: Cancer letters. Volume 362:Issue 2(2015)
• Page Start: 208
• Page End: 217
• Publication Date: 2015-07-01
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.03.041
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">MiR-30d-5p significantly inhibits the growth of NSCLC cells <italic>in vivo</italic>.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">MiR-30d-5p significantly inhibits invasion and migration of NSCLC cells <italic>in vitro</italic>.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">Cyclin E2 (CCNE2) is a direct functional target of miR-30d-5p in NSCLC cells.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">CCNE2 over-expression promotes the proliferation, invasion, and migration of NSCLC cells.</p> </list-item> </list> </p> </sec> </abstract>