Enantioselective Synthesis of Macrocyclic Heterobiaryl Derivatives of Molecular Asymmetry by Molybdenum‐Catalyzed Asymmetric Ring‐Closing Metathesis1. Issue 16 (23rd February 2015)

• Record Type: Journal Article
• Authors: Okayama, Yoichi; Tsuji, Satoru; Toyomori, Yuka; Mori, Atsunori; Arae, Sachie; Wu, Wei‐Yi; Takahashi, Tamotsu; Ogasawara, Masamichi
• Is Part Of: Angewandte Chemie international edition. Volume 54:Issue 16(2015)
• Page Start: 4927
• Page End: 4931
• Publication Date: 2015-02-23
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201500459
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Winding vine‐shaped molecular asymmetry is induced by enantioselective ring‐closing metathesis with a chiral molybdenum catalyst. The reaction proceeds under mild conditions through an <italic>E</italic>‐selective ring‐closing metathesis leading to macrocyclic bisazoles with enantioselectivities of up to 96 % <italic>ee</italic>.</p> </abstract>