No DDRama at chromosome ends: TRF2 takes centre stage. Issue 5 (May 2015)

• Record Type: Journal Article
• Authors: Feuerhahn, Sascha; Chen, Liuh-yow; Luke, Brian; Porro, Antonio
• Is Part Of: Trends in biochemical sciences. Volume 40:Issue 5(2015)
• Page Start: 275
• Page End: 285
• Publication Date: 2015-05
• Subjects: Biochemistry -- Periodicals; 572
• DOI: 10.1016/j.tibs.2015.03.003
• Languages: English
• ISSNs: 0968-0004

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Distinct molecular properties of TRF2 dictate different states of telomere protection.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">TRF2 promotes assembly of higher-order structures at telomeres.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">TRF2 remodels the telomeric chromatin environment.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">TRF2 regulates TERRA transcription.</p> </list-item> </list> </p> </sec> </abstract>