Design, synthesis and biological evaluation of novel peptide MC2 analogues from Momordica charantia as potential anti-diabetic agents1. Issue 15 (21st April 2015)

• Record Type: Journal Article
• Authors: Yang, Baowei; Li, Xue; Zhang, Chenyu; Yan, Sijia; Wei, Wei; Wang, Xuekun; Deng, Xin; Qian, Hai; Lin, Haiyan; Huang, Wenlong
• Is Part Of: Organic & biomolecular chemistry. Volume 13:Issue 15(2015)
• Page Start: 4551
• Page End: 4561
• Publication Date: 2015-04-21
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c5ob00333d
• Languages: English
• ISSNs: 1477-0520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjjh0zm44" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />The structure–activity relationship of peptide MC2 resulted in the development of compound <bold>III-3</bold>, which exhibited potent anti-hyperglycaemic and anti-oxidative effects.</p> </abstract>