Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers1. Issue 4 (16th April 2015)

• Record Type: Journal Article
• Authors: Azzarito, Valeria; Miles, Jennifer A.; Fisher, Julie; Edwards, Thomas A.; Warriner, Stuart L.; Wilson, Andrew J.
• Is Part Of: Chemical science. Volume 6:Issue 4(2015:Apr.)
• Page Start: 2434
• Page End: 2443
• Publication Date: 2015-04-16
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c4sc03559c
• Languages: English
• ISSNs: 2041-6520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjjgsn0f6" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />An oligoamide helix mimicking foldamer with well-defined conformation is shown to recognize its target protein <italic>h</italic>DM2 in a manner that depends upon the composition, spatial projection and stereochemistry of functional groups appended to the scaffold.</p> </abstract>