A hypoxia efficient imidazole-based Ru(ii) arene anticancer agent resistant to deactivation by glutathione1. Issue 13 (7th April 2015)

• Record Type: Journal Article
• Authors: Purkait, Kallol; Karmakar, Subhendu; Bhattacharyya, Sudipta; Chatterjee, Saptarshi; Dey, Suman Kr; Mukherjee, Arindam
• Is Part Of: Dalton transactions. Volume 44:Issue 13(2015)
• Page Start: 5969
• Page End: 5973
• Publication Date: 2015-04-07
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c4dt03983a
• Languages: English
• ISSNs: 1477-9226

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjjgsc3f2" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />[Ru^II(<italic>η</italic>⁶-<italic>p</italic>-cym)(L)Cl](PF₆) is slow to hydrolyze and shows better anticancer activity in hypoxia with strong resistance to deactivation by <sc>l</sc>-glutathione.</p> </abstract>