Enhanced uptake and siRNA-mediated knockdown of a biologically relevant gene using cyclodextrin polyrotaxane1. Issue 13 (7th April 2015)

• Record Type: Journal Article
• Authors: Dandekar, P.; Jain, R.; Keil, M.; Loretz, B.; Koch, M.; Wenz, G.; Lehr, C.-M.
• Is Part Of: Journal of materials chemistry. Volume 3:Issue 13(2015)
• Page Start: 2590
• Page End: 2598
• Publication Date: 2015-04-07
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c4tb01821d
• Languages: English
• ISSNs: 2050-750X

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjjgrb5ww" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Cellular investigations confirm the ability of cyclodextrin polyrotaxane nanoplexes to deliver siRNA for down-regulating genes relevant to the pathogenesis of tuberculosis.</p> </abstract>