Dimer domain swapping versus monomer folding in apo-myoglobin studied by molecular simulations. Issue 7 (21st February 2015)

• Record Type: Journal Article
• Authors: Ono, Koji; Ito, Mashiho; Hirota, Shun; Takada, Shoji
• Is Part Of: Physical chemistry chemical physics. Volume 17:Issue 7(2015)
• Page Start: 5006
• Page End: 5013
• Publication Date: 2015-02-21
• Subjects: Chemistry, Physical and theoretical -- Periodicals; 541.3
• DOI: 10.1039/c4cp05203j
• Languages: English
• ISSNs: 1463-9076

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjjgmn1d3" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Using a coarse-grained symmetrized Go model, we performed a series of folding simulations of two apo-myoglobin molecules restrained at a high density, addressing competition of formation of a domain-swapped dimer with folding to two monomer structures.</p> </abstract>