Physical Activity and Chronic Prostatitis/Chronic Pelvic Pain Syndrome. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: ZHANG, RAN; CHOMISTEK, ANDREA K.; DIMITRAKOFF, JORDAN D.; GIOVANNUCCI, EDWARD L.; WILLETT, WALTER C.; ROSNER, BERNARD A.; WU, KANA
• Is Part Of: Medicine and science in sports and exercise. Volume 47:Issue 4(2015)
• Publication Date: 2015-04
• Subjects: Sports medicine -- Periodicals; Exercise -- Physiological aspects -- Periodicals; Exercise -- Health aspects -- Periodicals; 612.044
• DOI: 10.1249/MSS.0000000000000472
• Languages: English
• ISSNs: 0195-9131

Abstract

<abstract> <title>ABSTRACT</title> <sec> <title>Purpose</title> <p>Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent urologic disorder among men, but its etiology is still poorly understood. Our objective was to examine the relation between physical activity and incidence of CP/CPPS in a large cohort of male health professionals.</p> </sec> <sec> <title>Methods</title> <p>We conducted a prospective cohort study among men in the Health Professionals Follow-up Study followed from 1986 to 2008. The study population included 20, 918 men who completed all CP/CPPS questions on the 2008 questionnaire. Leisure-time physical activity, including type and intensity of activity, was measured by questionnaire in 1986. A National Institute of Health Chronic Prostatitis Symptom Index pain score was calculated on the basis of the responses on the 2008 questionnaire. Participants with pain scores ≥8 were considered CP/CPPS cases (<italic>n</italic> = 689).</p> </sec> <sec> <title>Results</title> <p>Higher leisure-time physical activity was associated with lower risk of CP/CPPS. The multivariable-adjusted odds ratio comparing >35.0 to ⩽3.5 MET·h·wk<sup>−1</sup> of physical activity was 0.72 (95% confidence interval, 0.56–0.92; <italic>P</italic> for trend <0.001). Observed inverse associations between physical activity and CP/CPPS were similar for both moderate- and vigorous-intensity activities. Sedentary behavior, measured as time spent watching television, was not associated with risk of CP/CPPS (<italic>P</italic> for trend = 0.64).</p> </sec> <sec> <title>Conclusions</title> <p>Findings from this study, the first large scale and most comprehensive study to date on this association, suggest that higher levels of leisure-time physical activity may lower risk of CP/CPPS in middle-age and older men.</p> </sec> </abstract>