0.9% Saline Induced Hyperchloremic Acidosis. Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Barker, Megan E.
• Is Part Of: Journal of trauma nursing. Volume 22:Issue 2(2015)
• Publication Date: 2015-03
• Subjects: Emergency nursing -- Periodicals; Emergencies -- Nursing -- Periodicals; Soins infirmiers en situation d'urgence -- Périodiques; Lésions et blessures -- Périodiques; Emergencies -- nursing -- Periodicals; Wounds and Injuries -- nursing -- Periodicals; Nursing -- Periodicals; Traumatology -- Periodicals; Societies, Nursing -- Periodicals; 610.73
• DOI: 10.1097/JTN.0000000000000115
• Languages: English
• ISSNs: 1078-7496

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <p>In the acute care setting, the type and amount of fluid administered has a significant impact on patient outcomes. In particular, 0.9% saline infusions are known to cause or exacerbate hyperchloremia. The studies presented evaluate possible complications from 0.9% saline infusions. These studies compared administration of 0.9% saline with lactated ringer or plasmalyte in the acute care setting. In each trial, the patients who were randomized to receive 0.9% saline infusions had a more severe acidosis from increased serum chloride levels. From the available data, chloride-restrictive intravenous fluid such as plasmalyte appears to reduce acid-base disturbances and improve patient outcomes.</p> </sec> </abstract>