Fluorothymidine PET/CT in Neurolymphomatosis. (May 2015)

• Record Type: Journal Article
• Authors: Biswal, Chinmoy Kumar; Mittal, Bhagwant Rai; Shukla, Jaya; Vatsa, Rakhee; Bhattacharya, Anish; Prabhakar, Sudesh
• Is Part Of: Clinical nuclear medicine. Volume 40:Number 5(2015)
• Publication Date: 2015-05
• Subjects: Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000000632
• Languages: English
• ISSNs: 0363-9762

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title>Abstract</title> <p>Neurolymphomatosis, a rare extranodal lymphoma, may involve the cranial nerves, peripheral nerves, spinal nerve roots, or nerve plexus. ¹⁸F-FDG PET/CT however shows increased FDG uptake in the nerves but is not specific for malignancy. We report a patient with neurolymphomatosis who underwent ¹⁸F-FDG PET/CT and ¹⁸F-fluorothymidine PET/CT where both the scans showed increased tracer uptake in the right sciatic nerve, proven later as neurolymphomatosis on nerve biopsy. Furthermore, the ¹⁸F-FDG avid mediastinal lymph nodes did not show ¹⁸F-fluorothymidine avidity, suggesting an inflammatory etiology.</p> </sec> </abstract>