Curcumin attenuates cardiomyocyte hypertrophy induced by high glucose and insulin via the PPARγ/Akt/NO signaling pathway. Issue 2 (May 2015)

• Record Type: Journal Article
• Authors: Chen, Rongchun; Peng, Xiaofeng; Du, Weimin; Wu, Yang; Huang, Bo; Xue, Lai; Wu, Qin; Qiu, Hongmei; Jiang, Qingsong
• Is Part Of: Diabetes research and clinical practice. Volume 108:Issue 2(2015)
• Page Start: 235
• Page End: 242
• Publication Date: 2015-05
• Subjects: Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2015.02.012
• Languages: English
• ISSNs: 0168-8227

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">The mechanism of diabetic cardiomyopathy is still unclear.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">We made an <italic>in vitro</italic> diabetic cardiac hypertrophy model with HGI.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">We found PPARg/Akt/NO signal pathway was involved in diabetic cardiac hypertrophy.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Curcumin attenuates cardiac hypertrophy induced by HGI <italic>via</italic> this pathway.</p> </list-item> </list> </p> </sec> </abstract>