Aberrant expression of the CHFR prophase checkpoint gene in human B-cell non-Hodgkin lymphoma. Issue 5 (May 2015)

• Record Type: Journal Article
• Authors: Song, Aiqin; Ye, Junli; Zhang, Kunpeng; Yu, Hongsheng; Gao, Yanhua; Wang, Hongfang; Sun, Lirong; Xing, Xiaoming; Yang, Kun; Zhao, Min
• Is Part Of: Leukemia research. Volume 39:Issue 5(2015:May)
• Page Start: 536
• Page End: 543
• Publication Date: 2015-05
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.02.007
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">The expression of CHFR was reduced in B-NHL tissue samples and B cell lines.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">CHFR methylation correlated with CHFR downregulation and progression for B-NHL.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0020">Demethylation reagent, 5-Aza-dC or CHFR overexpression inhibited B cell growth.</p> </list-item> </list> </p> </sec> </abstract>